Organellar proteomics: the prizes and pitfalls of opening the nuclear envelope

Proteomic studies have the potential to comprehensively define the composition of organelles but are limited by the organellar cross-contamination that arises during subcellular fractionation. Comparative proteomics of organellar subfractions can mitigate these problems, as demonstrated by a recent...

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Detalles Bibliográficos
Autores principales: Schirmer, Eric C, Gerace, Larry
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139347/
https://www.ncbi.nlm.nih.gov/pubmed/11983061
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author Schirmer, Eric C
Gerace, Larry
author_facet Schirmer, Eric C
Gerace, Larry
author_sort Schirmer, Eric C
collection PubMed
description Proteomic studies have the potential to comprehensively define the composition of organelles but are limited by the organellar cross-contamination that arises during subcellular fractionation. Comparative proteomics of organellar subfractions can mitigate these problems, as demonstrated by a recent study involving the nuclear envelope.
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spelling pubmed-1393472003-03-03 Organellar proteomics: the prizes and pitfalls of opening the nuclear envelope Schirmer, Eric C Gerace, Larry Genome Biol Minireview Proteomic studies have the potential to comprehensively define the composition of organelles but are limited by the organellar cross-contamination that arises during subcellular fractionation. Comparative proteomics of organellar subfractions can mitigate these problems, as demonstrated by a recent study involving the nuclear envelope. BioMed Central 2002 2002-03-13 /pmc/articles/PMC139347/ /pubmed/11983061 Text en Copyright © 2002 BioMed Central Ltd
spellingShingle Minireview
Schirmer, Eric C
Gerace, Larry
Organellar proteomics: the prizes and pitfalls of opening the nuclear envelope
title Organellar proteomics: the prizes and pitfalls of opening the nuclear envelope
title_full Organellar proteomics: the prizes and pitfalls of opening the nuclear envelope
title_fullStr Organellar proteomics: the prizes and pitfalls of opening the nuclear envelope
title_full_unstemmed Organellar proteomics: the prizes and pitfalls of opening the nuclear envelope
title_short Organellar proteomics: the prizes and pitfalls of opening the nuclear envelope
title_sort organellar proteomics: the prizes and pitfalls of opening the nuclear envelope
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139347/
https://www.ncbi.nlm.nih.gov/pubmed/11983061
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