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Founder populations and their uses for breast cancer genetics
Numerous founder mutations have been reported in BRCA1 and BRCA2. For genetic screening of a population with a founder mutation, testing can be targeted to the mutation, allowing for a more rapid and less expensive test. In addition, more precise estimates of the prior probability of carrying a muta...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2000
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139426/ https://www.ncbi.nlm.nih.gov/pubmed/11250694 http://dx.doi.org/10.1186/bcr36 |