Genetic reduction of chronic muscle pain in mice lacking calcium/calmodulin-stimulated adenylyl cyclases

BACKGROUND: The Ca(2+)/calmodulin-stimulated adenylyl cyclase (AC) isoforms AC1 and AC8, couple NMDA receptor activation to cAMP signaling pathways in neurons and are important for development, learning and memory, drug addiction and persistent pain. AC1 and AC8 in the anterior cingulate cortex (ACC...

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Detalles Bibliográficos
Autores principales: Vadakkan, Kunjumon I, Wang, Hansen, Ko, Shanelle W, Zastepa, Evelyn, Petrovic, Michele J, Sluka, Kathleen A, Zhuo, Min
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1395303/
https://www.ncbi.nlm.nih.gov/pubmed/16503978
http://dx.doi.org/10.1186/1744-8069-2-7

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