Modeling the bound conformation of Pemphigus Vulgaris-associated peptides to MHC Class II DR and DQ Alleles

BACKGROUND: Pemphigus vulgaris (PV) is a severe autoimmune blistering disorder characterized by the presence of pathogenic autoantibodies directed against desmoglein-3 (Dsg3), involving specific DR4 and DR6 alleles in Caucasians and DQ5 allele in Asians. The development of sequence-based predictive...

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Detalles Bibliográficos
Autores principales: Tong, Joo Chuan, Bramson, Jeff, Kanduc, Darja, Chow, Selwyn, Sinha, Animesh A, Ranganathan, Shoba
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1395305/
https://www.ncbi.nlm.nih.gov/pubmed/16426456
http://dx.doi.org/10.1186/1745-7580-2-1

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