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Ca(2+)-signaling in airway smooth muscle cells is altered in T-bet knock-out mice

BACKGROUND: Airway smooth muscle cells (ASMC) play a key role in bronchial hyperresponsiveness (BHR). A major component of the signaling cascade leading to ASMC contraction is calcium. So far, agonist-induced Ca(2+)-signaling in asthma has been studied by comparing innate properties of inbred rat or...

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Detalles Bibliográficos
Autores principales: Bergner, Albrecht, Kellner, Julia, Kemp da Silva, Anita, Gamarra, Fernando, Huber, Rudolf M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1395308/
https://www.ncbi.nlm.nih.gov/pubmed/16504082
http://dx.doi.org/10.1186/1465-9921-7-33