Wnt signalling in lung development and diseases

There are several signalling pathways involved in lung organogenesis including Notch, TGFβ /BMP, Sonic hedgehog (Shh), FGF, EGF, and Wnt. Despite the widely acknowledged significance of Wnt signalling in embryonic lung development, the role of different Wnt pathways in lung pathologies has been slow...

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Detalles Bibliográficos
Autores principales: Pongracz, Judit E, Stockley, Robert A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1397816/
https://www.ncbi.nlm.nih.gov/pubmed/16438732
http://dx.doi.org/10.1186/1465-9921-7-15
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author Pongracz, Judit E
Stockley, Robert A
author_facet Pongracz, Judit E
Stockley, Robert A
author_sort Pongracz, Judit E
collection PubMed
description There are several signalling pathways involved in lung organogenesis including Notch, TGFβ /BMP, Sonic hedgehog (Shh), FGF, EGF, and Wnt. Despite the widely acknowledged significance of Wnt signalling in embryonic lung development, the role of different Wnt pathways in lung pathologies has been slow to emerge. In this review, we will present a synopsis of current Wnt research with particular attention paid to the role of Wnt signals in lung development and in pulmonary diseases.
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spelling pubmed-13978162006-03-11 Wnt signalling in lung development and diseases Pongracz, Judit E Stockley, Robert A Respir Res Review There are several signalling pathways involved in lung organogenesis including Notch, TGFβ /BMP, Sonic hedgehog (Shh), FGF, EGF, and Wnt. Despite the widely acknowledged significance of Wnt signalling in embryonic lung development, the role of different Wnt pathways in lung pathologies has been slow to emerge. In this review, we will present a synopsis of current Wnt research with particular attention paid to the role of Wnt signals in lung development and in pulmonary diseases. BioMed Central 2006 2006-01-26 /pmc/articles/PMC1397816/ /pubmed/16438732 http://dx.doi.org/10.1186/1465-9921-7-15 Text en Copyright © 2006 Pongracz and Stockley; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Pongracz, Judit E
Stockley, Robert A
Wnt signalling in lung development and diseases
title Wnt signalling in lung development and diseases
title_full Wnt signalling in lung development and diseases
title_fullStr Wnt signalling in lung development and diseases
title_full_unstemmed Wnt signalling in lung development and diseases
title_short Wnt signalling in lung development and diseases
title_sort wnt signalling in lung development and diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1397816/
https://www.ncbi.nlm.nih.gov/pubmed/16438732
http://dx.doi.org/10.1186/1465-9921-7-15
work_keys_str_mv AT pongraczjudite wntsignallinginlungdevelopmentanddiseases
AT stockleyroberta wntsignallinginlungdevelopmentanddiseases

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