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Methods for the synthesis of polyhydroxylated piperidines by diastereoselective dihydroxylation: Exploitation in the two-directional synthesis of aza-C-linked disaccharide derivatives
BACKGROUND: Many polyhydroxylated piperidines are inhibitors of the oligosaccharide processing enzymes, glycosidases and glycosyltransferases. Aza-C-linked disaccharide mimetics are compounds in which saturated polyhydroxylated nitrogen and oxygen heterocycles are linked by an all-carbon tether. The...
Autores principales: | Kennedy, Andrew, Nelson, Adam, Perry, Alexis |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1399450/ https://www.ncbi.nlm.nih.gov/pubmed/16542015 http://dx.doi.org/10.1186/1860-5397-1-2 |
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