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Cobalt(II) chloride catalyzed one-pot synthesis of α-aminonitriles
A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three- component condensation of aldehydes, amines, and potassium cyanide in acetonitrile in the presence of a catalytic amount of CoCl(2) at room temperature.
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1399456/ https://www.ncbi.nlm.nih.gov/pubmed/16542021 http://dx.doi.org/10.1186/1860-5397-1-8 |
| Sumario: | A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three- component condensation of aldehydes, amines, and potassium cyanide in acetonitrile in the presence of a catalytic amount of CoCl(2) at room temperature. |
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