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Cobalt(II) chloride catalyzed one-pot synthesis of α-aminonitriles
A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three- component condensation of aldehydes, amines, and potassium cyanide in acetonitrile in the presence of a catalytic amount of CoCl(2) at room temperature.
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| Formato: | Texto |
| Lenguaje: | English |
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Beilstein-Institut
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1399456/ https://www.ncbi.nlm.nih.gov/pubmed/16542021 http://dx.doi.org/10.1186/1860-5397-1-8 |
| _version_ | 1782126988629114880 |
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| author | De, Surya K |
| author_facet | De, Surya K |
| author_sort | De, Surya K |
| collection | PubMed |
| description | A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three- component condensation of aldehydes, amines, and potassium cyanide in acetonitrile in the presence of a catalytic amount of CoCl(2) at room temperature. |
| format | Text |
| id | pubmed-1399456 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2005 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-13994562006-03-13 Cobalt(II) chloride catalyzed one-pot synthesis of α-aminonitriles De, Surya K Beilstein J Org Chem Full Research Paper A simple and efficient method has been developed for the synthesis of α-aminonitriles by a one-pot three- component condensation of aldehydes, amines, and potassium cyanide in acetonitrile in the presence of a catalytic amount of CoCl(2) at room temperature. Beilstein-Institut 2005-10-07 /pmc/articles/PMC1399456/ /pubmed/16542021 http://dx.doi.org/10.1186/1860-5397-1-8 Text en Copyright © 2005, De https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Full Research Paper De, Surya K Cobalt(II) chloride catalyzed one-pot synthesis of α-aminonitriles |
| title | Cobalt(II) chloride catalyzed one-pot synthesis of α-aminonitriles |
| title_full | Cobalt(II) chloride catalyzed one-pot synthesis of α-aminonitriles |
| title_fullStr | Cobalt(II) chloride catalyzed one-pot synthesis of α-aminonitriles |
| title_full_unstemmed | Cobalt(II) chloride catalyzed one-pot synthesis of α-aminonitriles |
| title_short | Cobalt(II) chloride catalyzed one-pot synthesis of α-aminonitriles |
| title_sort | cobalt(ii) chloride catalyzed one-pot synthesis of α-aminonitriles |
| topic | Full Research Paper |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1399456/ https://www.ncbi.nlm.nih.gov/pubmed/16542021 http://dx.doi.org/10.1186/1860-5397-1-8 |
| work_keys_str_mv | AT desuryak cobaltiichloridecatalyzedonepotsynthesisofaaminonitriles |