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Towards practical biocatalytic Baeyer-Villiger reactions: applying a thermostable enzyme in the gram-scale synthesis of optically-active lactones in a two-liquid-phase system
Baeyer-Villiger monooxygenases (BVMOs) are extremely promising catalysts useful for enantioselective oxidation reactions of ketones, but organic chemists have not used them widely due to several reasons. These include instability of the enzymes in the case of in vitro and even in vivo systems, react...
Autores principales: | Schulz, Frank, Leca, François, Hollmann, Frank, Reetz, Manfred T |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1399458/ https://www.ncbi.nlm.nih.gov/pubmed/16542025 http://dx.doi.org/10.1186/1860-5397-1-10 |
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