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Increased expression of AP2 and Sp1 transcription factors in human thyroid tumors: a role in NIS expression regulation?
BACKGROUND: Sodium/iodide symporter (NIS) is a key protein in iodide transport by thyroid cells and this activity is a prerequisite for effective radioiodide treatment of thyroid cancer. In the majority of thyroid cancers, however, iodide uptake is reduced, probably as a result of decreased NIS prot...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139985/ https://www.ncbi.nlm.nih.gov/pubmed/12475396 http://dx.doi.org/10.1186/1471-2407-2-35 |