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Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes
BACKGROUND: Immature B lymphocytes and certain B cell lymphomas undergo apoptotic cell death following activation of the B cell antigen receptor (BCR) signal transduction pathway. Several biochemical changes occur in response to BCR engagement, including activation of the Syk tyrosine kinase. Althou...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2002
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139997/ https://www.ncbi.nlm.nih.gov/pubmed/12470302 http://dx.doi.org/10.1186/1471-2172-3-16 |