Expression and function profiling of orphan nuclear receptors using bacterial artificial chromosome (BAC) transgenesis.

The long term goal of the Nuclear Receptor Signaling Atlas (NURSA) resides in unraveling the physiological and pathological functions of nuclear receptors (NRs) at the molecular, biochemical and cellular levels. This multi-oriented task requires complementary approaches in order to determine the spe...

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Detalles Bibliográficos
Autores principales: Nemoz-Gaillard, Eric, Tsai, Ming-Jer, Tsai, Sophia Y.
Formato: Texto
Lenguaje:English
Publicado: The Nuclear Receptor Signaling Atlas 2003
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402220/
https://www.ncbi.nlm.nih.gov/pubmed/16604177
http://dx.doi.org/10.1621/nrs.01005
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author Nemoz-Gaillard, Eric
Tsai, Ming-Jer
Tsai, Sophia Y.
author_facet Nemoz-Gaillard, Eric
Tsai, Ming-Jer
Tsai, Sophia Y.
author_sort Nemoz-Gaillard, Eric
collection PubMed
description The long term goal of the Nuclear Receptor Signaling Atlas (NURSA) resides in unraveling the physiological and pathological functions of nuclear receptors (NRs) at the molecular, biochemical and cellular levels. This multi-oriented task requires complementary approaches in order to determine the specific function(s) and precise expression and receptor activity patterns for each individual conventional or orphan receptor. To attain this objective, we have chose to turn to technologies recently made available to engineer bacterial artificial chromosomes (BACs).
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spelling pubmed-14022202006-04-06 Expression and function profiling of orphan nuclear receptors using bacterial artificial chromosome (BAC) transgenesis. Nemoz-Gaillard, Eric Tsai, Ming-Jer Tsai, Sophia Y. Nucl Recept Signal Perspective The long term goal of the Nuclear Receptor Signaling Atlas (NURSA) resides in unraveling the physiological and pathological functions of nuclear receptors (NRs) at the molecular, biochemical and cellular levels. This multi-oriented task requires complementary approaches in order to determine the specific function(s) and precise expression and receptor activity patterns for each individual conventional or orphan receptor. To attain this objective, we have chose to turn to technologies recently made available to engineer bacterial artificial chromosomes (BACs). The Nuclear Receptor Signaling Atlas 2003-06-16 /pmc/articles/PMC1402220/ /pubmed/16604177 http://dx.doi.org/10.1621/nrs.01005 Text en Copyright © 2003, Nemoz-Gailliard et al. This is an open-access article distributed under the terms of the Creative Commons Non-Commercial Attribution License, which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Perspective
Nemoz-Gaillard, Eric
Tsai, Ming-Jer
Tsai, Sophia Y.
Expression and function profiling of orphan nuclear receptors using bacterial artificial chromosome (BAC) transgenesis.
title Expression and function profiling of orphan nuclear receptors using bacterial artificial chromosome (BAC) transgenesis.
title_full Expression and function profiling of orphan nuclear receptors using bacterial artificial chromosome (BAC) transgenesis.
title_fullStr Expression and function profiling of orphan nuclear receptors using bacterial artificial chromosome (BAC) transgenesis.
title_full_unstemmed Expression and function profiling of orphan nuclear receptors using bacterial artificial chromosome (BAC) transgenesis.
title_short Expression and function profiling of orphan nuclear receptors using bacterial artificial chromosome (BAC) transgenesis.
title_sort expression and function profiling of orphan nuclear receptors using bacterial artificial chromosome (bac) transgenesis.
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402220/
https://www.ncbi.nlm.nih.gov/pubmed/16604177
http://dx.doi.org/10.1621/nrs.01005
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AT tsaimingjer expressionandfunctionprofilingoforphannuclearreceptorsusingbacterialartificialchromosomebactransgenesis
AT tsaisophiay expressionandfunctionprofilingoforphannuclearreceptorsusingbacterialartificialchromosomebactransgenesis

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