Cardiovascular roles of estrogen receptors: insights gained from knockout models

The effects of estrogen are mediated through two functionally distinct receptors, estrogen receptor α (ER- α ), and estrogen receptor β (ER- β ), both of which are expressed in the cardiovascular system. The etiology of cardiovascular disease is believed to result in part from the loss of endogenous...

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Detalles Bibliográficos
Autores principales: Otsuki, Michio, Dahlman-Wright, Karin, Gustafsson, Jan-Äke
Formato: Texto
Lenguaje:English
Publicado: The Nuclear Receptor Signaling Atlas 2003
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402221/
https://www.ncbi.nlm.nih.gov/pubmed/16604173
http://dx.doi.org/10.1621/nrs.01003
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author Otsuki, Michio
Dahlman-Wright, Karin
Gustafsson, Jan-Äke
author_facet Otsuki, Michio
Dahlman-Wright, Karin
Gustafsson, Jan-Äke
author_sort Otsuki, Michio
collection PubMed
description The effects of estrogen are mediated through two functionally distinct receptors, estrogen receptor α (ER- α ), and estrogen receptor β (ER- β ), both of which are expressed in the cardiovascular system. The etiology of cardiovascular disease is believed to result in part from the loss of endogenous estrogen, indicating that estrogen and its receptors may play important roles in the prevention of cardiovascular disease in women.
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spelling pubmed-14022212006-04-06 Cardiovascular roles of estrogen receptors: insights gained from knockout models Otsuki, Michio Dahlman-Wright, Karin Gustafsson, Jan-Äke Nucl Recept Signal Perspective The effects of estrogen are mediated through two functionally distinct receptors, estrogen receptor α (ER- α ), and estrogen receptor β (ER- β ), both of which are expressed in the cardiovascular system. The etiology of cardiovascular disease is believed to result in part from the loss of endogenous estrogen, indicating that estrogen and its receptors may play important roles in the prevention of cardiovascular disease in women. The Nuclear Receptor Signaling Atlas 2003-06-15 /pmc/articles/PMC1402221/ /pubmed/16604173 http://dx.doi.org/10.1621/nrs.01003 Text en Copyright©2003, Otsuki et al. This is an open-access article distributed under the terms of the Creative Commons Non-Commercial Attribution License, which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Perspective
Otsuki, Michio
Dahlman-Wright, Karin
Gustafsson, Jan-Äke
Cardiovascular roles of estrogen receptors: insights gained from knockout models
title Cardiovascular roles of estrogen receptors: insights gained from knockout models
title_full Cardiovascular roles of estrogen receptors: insights gained from knockout models
title_fullStr Cardiovascular roles of estrogen receptors: insights gained from knockout models
title_full_unstemmed Cardiovascular roles of estrogen receptors: insights gained from knockout models
title_short Cardiovascular roles of estrogen receptors: insights gained from knockout models
title_sort cardiovascular roles of estrogen receptors: insights gained from knockout models
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402221/
https://www.ncbi.nlm.nih.gov/pubmed/16604173
http://dx.doi.org/10.1621/nrs.01003
work_keys_str_mv AT otsukimichio cardiovascularrolesofestrogenreceptorsinsightsgainedfromknockoutmodels
AT dahlmanwrightkarin cardiovascularrolesofestrogenreceptorsinsightsgainedfromknockoutmodels
AT gustafssonjanake cardiovascularrolesofestrogenreceptorsinsightsgainedfromknockoutmodels

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