Sequentiality and processivity of nuclear receptor coregulators in regulation of target gene expression

A series of data has accumulated over the past five years that raises questions about our current understanding of the transcriptional process and its regulation. Following the discovery of coactivators for nuclear receptors (NRs), a large number of these molecules have been reported in the literatu...

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Detalles Bibliográficos
Autor principal: O'Malley, Bert W.
Formato: Texto
Lenguaje:English
Publicado: The Nuclear Receptor Signaling Atlas 2003
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402223/
https://www.ncbi.nlm.nih.gov/pubmed/16604182
http://dx.doi.org/10.1621/nrs.01010
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author O'Malley, Bert W.
author_facet O'Malley, Bert W.
author_sort O'Malley, Bert W.
collection PubMed
description A series of data has accumulated over the past five years that raises questions about our current understanding of the transcriptional process and its regulation. Following the discovery of coactivators for nuclear receptors (NRs), a large number of these molecules have been reported in the literature. This perspective will summarize some opinions on the significance of this large number of factors.
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spelling pubmed-14022232006-04-06 Sequentiality and processivity of nuclear receptor coregulators in regulation of target gene expression O'Malley, Bert W. Nucl Recept Signal Perspective A series of data has accumulated over the past five years that raises questions about our current understanding of the transcriptional process and its regulation. Following the discovery of coactivators for nuclear receptors (NRs), a large number of these molecules have been reported in the literature. This perspective will summarize some opinions on the significance of this large number of factors. The Nuclear Receptor Signaling Atlas 2003-10-25 /pmc/articles/PMC1402223/ /pubmed/16604182 http://dx.doi.org/10.1621/nrs.01010 Text en Copyright © 2003, O'Malley. This is an open-access article distributed under the terms of the Creative Commons Non-Commercial Attribution License, which permits unrestricted non-commercial use distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Perspective
O'Malley, Bert W.
Sequentiality and processivity of nuclear receptor coregulators in regulation of target gene expression
title Sequentiality and processivity of nuclear receptor coregulators in regulation of target gene expression
title_full Sequentiality and processivity of nuclear receptor coregulators in regulation of target gene expression
title_fullStr Sequentiality and processivity of nuclear receptor coregulators in regulation of target gene expression
title_full_unstemmed Sequentiality and processivity of nuclear receptor coregulators in regulation of target gene expression
title_short Sequentiality and processivity of nuclear receptor coregulators in regulation of target gene expression
title_sort sequentiality and processivity of nuclear receptor coregulators in regulation of target gene expression
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402223/
https://www.ncbi.nlm.nih.gov/pubmed/16604182
http://dx.doi.org/10.1621/nrs.01010
work_keys_str_mv AT omalleybertw sequentialityandprocessivityofnuclearreceptorcoregulatorsinregulationoftargetgeneexpression

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