Structural insights into regulation of nuclear receptors by ligands

Nuclear receptors are DNA-binding transcription factors, the transcriptional function of many of which depends on the binding of ligands, a feature that distinguishes nuclear receptors from other transcription factors. This review will summarize recent advances in our knowledge of the interaction be...

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Detalles Bibliográficos
Autores principales: Xu, Eric H., Lambert, Millard H.
Formato: Texto
Lenguaje:English
Publicado: The Nuclear Receptor Signaling Atlas 2003
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402225/
https://www.ncbi.nlm.nih.gov/pubmed/16604176
http://dx.doi.org/10.1621/nrs.01004
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author Xu, Eric H.
Lambert, Millard H.
author_facet Xu, Eric H.
Lambert, Millard H.
author_sort Xu, Eric H.
collection PubMed
description Nuclear receptors are DNA-binding transcription factors, the transcriptional function of many of which depends on the binding of ligands, a feature that distinguishes nuclear receptors from other transcription factors. This review will summarize recent advances in our knowledge of the interaction between selected nuclear receptors and their cognate ligands.
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spelling pubmed-14022252006-04-06 Structural insights into regulation of nuclear receptors by ligands Xu, Eric H. Lambert, Millard H. Nucl Recept Signal Review Nuclear receptors are DNA-binding transcription factors, the transcriptional function of many of which depends on the binding of ligands, a feature that distinguishes nuclear receptors from other transcription factors. This review will summarize recent advances in our knowledge of the interaction between selected nuclear receptors and their cognate ligands. The Nuclear Receptor Signaling Atlas 2003-06-15 /pmc/articles/PMC1402225/ /pubmed/16604176 http://dx.doi.org/10.1621/nrs.01004 Text en Copyright © 2003, Xu and Lambert. This is an open-access article distributed under the terms of the Creative Commons Non-Commercial Attribution License, which permits unrestricted non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Xu, Eric H.
Lambert, Millard H.
Structural insights into regulation of nuclear receptors by ligands
title Structural insights into regulation of nuclear receptors by ligands
title_full Structural insights into regulation of nuclear receptors by ligands
title_fullStr Structural insights into regulation of nuclear receptors by ligands
title_full_unstemmed Structural insights into regulation of nuclear receptors by ligands
title_short Structural insights into regulation of nuclear receptors by ligands
title_sort structural insights into regulation of nuclear receptors by ligands
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402225/
https://www.ncbi.nlm.nih.gov/pubmed/16604176
http://dx.doi.org/10.1621/nrs.01004
work_keys_str_mv AT xuerich structuralinsightsintoregulationofnuclearreceptorsbyligands
AT lambertmillardh structuralinsightsintoregulationofnuclearreceptorsbyligands

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