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Number of active transcription factor binding sites is essential for the Hes7 oscillator
BACKGROUND: It is commonly accepted that embryonic segmentation of vertebrates is regulated by a segmentation clock, which is induced by the cycling genes Hes1 and Hes7. Their products form dimers that bind to the regulatory regions and thereby repress the transcription of their own encoding genes....
Autores principales: | Zeiser, Stefan, Liebscher, H Volkmar, Tiedemann, Hendrik, Rubio-Aliaga, Isabel, Przemeck, Gerhard KH, de Angelis, Martin Hrabé, Winkler, Gerhard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402261/ https://www.ncbi.nlm.nih.gov/pubmed/16504083 http://dx.doi.org/10.1186/1742-4682-3-11 |
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