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The proximal promoter region of mTert is sufficient to regulate telomerase activity in ES cells and transgenic animals

BACKGROUND: The reverse transcriptase of telomerase (Tert) controls telomerase activity maintaining the end of linear chromosomes in eukaryotic cells. Telomerase function is highly active in undifferentiated multipotent stem cells, decreases with cell differentiation and is generally absent from mos...

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Detalles Bibliográficos
Autores principales:	Pericuesta, Eva, Ramírez, Miguel Angel, Villa-Diaz, Ana, Relaño-Gines, Aroa, Maria Torres, Juan, Nieto, Marta, Pintado, Belen, Gutiérrez-Adán, Alfonso
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402293/ https://www.ncbi.nlm.nih.gov/pubmed/16457732 http://dx.doi.org/10.1186/1477-7827-4-5

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