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Na(v )1.8-null mice show stimulus-dependent deficits in spinal neuronal activity
BACKGROUND: The voltage gated sodium channel Na(v )1.8 has a highly restricted expression pattern to predominantly nociceptive peripheral sensory neurones. Behaviourally Na(v )1.8-null mice show an increased acute pain threshold to noxious mechanical pressure and also deficits in inflammatory and vi...
Autores principales: | Matthews, Elizabeth A, Wood, John N, Dickenson, Anthony H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1403745/ https://www.ncbi.nlm.nih.gov/pubmed/16478543 http://dx.doi.org/10.1186/1744-8069-2-5 |
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