Efficient in vivo knock-down of estrogen receptor alpha: application of recombinant adenovirus vectors for delivery of short hairpin RNA

BACKGROUND: Adenovirus (Ad) mediated gene transfer is a well-established tool to transiently express constructs in livers of mice in vivo. In the present study, we determined the specificity and efficiency of Ad vectors expressing short hairpin (sh) RNA constructs to knock-down the estrogen receptor...

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Detalles Bibliográficos
Autores principales: Krom, Yvonne D, Fallaux, Frits J, Que, Ivo, Lowik, Clemens, van Dijk, Ko Willems
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1403768/
https://www.ncbi.nlm.nih.gov/pubmed/16507095
http://dx.doi.org/10.1186/1472-6750-6-11

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