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Role of the tryptophan residue in the vicinity of the catalytic center of exonuclease III family AP endonucleases: AP site recognition mechanism

The mechanisms by which AP endonucleases recognize AP sites have not yet been determined. Based on our previous study with Escherichia coli exonuclease III (ExoIII), the ExoIII family AP endonucleases probably recognize the DNA-pocket formed at an AP site. The indole ring of a conserved tryptophan r...

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Detalles Bibliográficos
Autores principales:	Kaneda, Kohichi, Sekiguchi, Junichi, Shida, Toshio
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1408312/ https://www.ncbi.nlm.nih.gov/pubmed/16540594 http://dx.doi.org/10.1093/nar/gkl059

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