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Genetic polymorphisms in human SULT1A1 and UGT1A1 genes associate with breast tumor characteristics: a case-series study

INTRODUCTION: Estrogens are important in breast cancer development. SULT1A1 and UGT1A1 catalyze estrogen metabolism and are polymorphic. The SULT1A1*2 protein exhibits low activity, and a TA repeat within the UGT1A1 promoter alters the level of expression of the protein. We hypothesized that the SUL...

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Detalles Bibliográficos
Autores principales:	Shatalova, Ekaterina G, Walther, Susan E, Favorova, Olga O, Rebbeck, Timothy R, Blanchard, Rebecca L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1410736/ https://www.ncbi.nlm.nih.gov/pubmed/16280036 http://dx.doi.org/10.1186/bcr1318

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