The estrogen receptor-α A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study

INTRODUCTION: Evidence suggests that alterations in estrogen signaling pathways, including estrogen receptor-α (ER-α), occur during breast cancer development. A point mutation in ER-α (nucleotide A908G), producing an amino acid change from lysine to arginine at codon 303 (K303R) results in receptor...

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Detalles Bibliográficos
Autores principales: Conway, Kathleen, Parrish, Eloise, Edmiston, Sharon N, Tolbert, Dawn, Tse, Chiu-Kit, Geradts, Joseph, Livasy, Chad A, Singh, Harsharan, Newman, Beth, Millikan, Robert C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1410768/
https://www.ncbi.nlm.nih.gov/pubmed/16280033
http://dx.doi.org/10.1186/bcr1315

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