A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks

BACKGROUND: Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinatorial explosion of different states generated by feasible molecular species. The number of possible species grows exponent...

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Detalles Bibliográficos
Autores principales: Conzelmann, Holger, Saez-Rodriguez, Julio, Sauter, Thomas, Kholodenko, Boris N, Gilles, Ernst D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413560/
https://www.ncbi.nlm.nih.gov/pubmed/16430778
http://dx.doi.org/10.1186/1471-2105-7-34

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