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Splicing regulators: targets and drugs

Silencing of splicing regulators by RNA interference, combined with splicing-specific microarrays, has revealed a complex network of distinct alternative splicing events in Drosophila, while a high-throughput screen of more than 6,000 compounds has identified drugs that interfere specifically and di...

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Detalles Bibliográficos
Autor principal: Yeo, Gene Wei-Ming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1414078/
https://www.ncbi.nlm.nih.gov/pubmed/16356274
http://dx.doi.org/10.1186/gb-2005-6-12-240
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author Yeo, Gene Wei-Ming
author_facet Yeo, Gene Wei-Ming
author_sort Yeo, Gene Wei-Ming
collection PubMed
description Silencing of splicing regulators by RNA interference, combined with splicing-specific microarrays, has revealed a complex network of distinct alternative splicing events in Drosophila, while a high-throughput screen of more than 6,000 compounds has identified drugs that interfere specifically and directly with one class of splicing regulators in human cells.
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spelling pubmed-14140782006-03-28 Splicing regulators: targets and drugs Yeo, Gene Wei-Ming Genome Biol Minireview Silencing of splicing regulators by RNA interference, combined with splicing-specific microarrays, has revealed a complex network of distinct alternative splicing events in Drosophila, while a high-throughput screen of more than 6,000 compounds has identified drugs that interfere specifically and directly with one class of splicing regulators in human cells. BioMed Central 2005 2005-12-01 /pmc/articles/PMC1414078/ /pubmed/16356274 http://dx.doi.org/10.1186/gb-2005-6-12-240 Text en Copyright © 2005 BioMed Central Ltd
spellingShingle Minireview
Yeo, Gene Wei-Ming
Splicing regulators: targets and drugs
title Splicing regulators: targets and drugs
title_full Splicing regulators: targets and drugs
title_fullStr Splicing regulators: targets and drugs
title_full_unstemmed Splicing regulators: targets and drugs
title_short Splicing regulators: targets and drugs
title_sort splicing regulators: targets and drugs
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1414078/
https://www.ncbi.nlm.nih.gov/pubmed/16356274
http://dx.doi.org/10.1186/gb-2005-6-12-240
work_keys_str_mv AT yeogeneweiming splicingregulatorstargetsanddrugs