Search for genetic variants in the p66(Shc )longevity gene by PCR-single strand conformational polymorphism in patients with early-onset cardiovascular disease

BACKGROUND: Among the possible candidate genes for atherosclerosis experimental data point towards the longevity gene p66(Shc). The p66(Shc )gene determines an increase of intracellular reactive oxygen species (ROS), affecting the rate of oxidative damage to nucleic acids. Knock-out p66(Shc-/- )mice...

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Detalles Bibliográficos
Autores principales: Sentinelli, Federica, Romeo, Stefano, Barbetti, Fabrizio, Berni, Andrea, Filippi, Emanuela, Fanelli, Marzia, Fallarino, Mara, Baroni, Marco G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420326/
https://www.ncbi.nlm.nih.gov/pubmed/16519809
http://dx.doi.org/10.1186/1471-2156-7-14

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