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Distance determination by GIY-YIG intron endonucleases: discrimination between repression and cleavage functions

GIY-YIG homing endonucleases are modular proteins, with conserved N-terminal catalytic domains connected by linkers to C-terminal DNA-binding domains. I-TevI, the T4 phage GIY-YIG intron endonuclease, functions both in promoting td intron homing, and in acting as a transcriptional autorepressor. Rep...

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Detalles Bibliográficos
Autores principales: Liu, Qingqing, Derbyshire, Victoria, Belfort, Marlene, Edgell, David R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1421500/
https://www.ncbi.nlm.nih.gov/pubmed/16582101
http://dx.doi.org/10.1093/nar/gkl079

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