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Loss of LIN-35, the Caenorhabditis elegans ortholog of the tumor suppressor p105Rb, results in enhanced RNA interference

BACKGROUND: Genome-wide RNA interference (RNAi) screening is a very powerful tool for analyzing gene function in vivo in Caenorhabditis elegans. The effectiveness of RNAi varies from gene to gene, however, and neuronally expressed genes are largely refractive to RNAi in wild-type worms. RESULTS: We...

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Detalles Bibliográficos
Autores principales:	Lehner, Ben, Calixto, Andrea, Crombie, Catriona, Tischler, Julia, Fortunato, Angelo, Chalfie, Martin, Fraser, Andrew G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431716/ https://www.ncbi.nlm.nih.gov/pubmed/16507136 http://dx.doi.org/10.1186/gb-2006-7-1-r4

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