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Predicting genes for orphan metabolic activities using phylogenetic profiles
Homology-based methods fail to assign genes to many metabolic activities present in sequenced organisms. To suggest genes for these orphan activities we developed a novel method that efficiently combines local structure of a metabolic network with phylogenetic profiles. We validated our method using...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1431735/ https://www.ncbi.nlm.nih.gov/pubmed/16507154 http://dx.doi.org/10.1186/gb-2006-7-2-r17 |