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Corticosteroid co-treatment induces resistance to chemotherapy in surgical resections, xenografts and established cell lines of pancreatic cancer
BACKGROUND: Chemotherapy for pancreatic carcinoma often has severe side effects that limit its efficacy. The glucocorticoid (GC) dexamethasone (DEX) is frequently used as co-treatment to prevent side effects of chemotherapy such as nausea, for palliative purposes and to treat allergic reactions. Whi...
Autores principales: | Zhang, Chengwen, Kolb, Armin, Büchler, Peter, Cato, Andrew CB, Mattern, Jürgen, Rittgen, Werner, Edler, Lutz, Debatin, Klaus-Michael, Büchler, Markus W, Friess, Helmut, Herr, Ingrid |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434760/ https://www.ncbi.nlm.nih.gov/pubmed/16539710 http://dx.doi.org/10.1186/1471-2407-6-61 |
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