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Development of an unbiased statistical method for the analysis of unigenic evolution

BACKGROUND: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This method involves selection of variants of the protein which retain function, followed by statistical analysis comparing ex...

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Detalles Bibliográficos
Autores principales: Behrsin, Colleen D, Brandl, Chris J, Litchfield, David W, Shilton, Brian H, Wahl, Lindi M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434776/
https://www.ncbi.nlm.nih.gov/pubmed/16545116
http://dx.doi.org/10.1186/1471-2105-7-150