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Development of an unbiased statistical method for the analysis of unigenic evolution
BACKGROUND: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This method involves selection of variants of the protein which retain function, followed by statistical analysis comparing ex...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434776/ https://www.ncbi.nlm.nih.gov/pubmed/16545116 http://dx.doi.org/10.1186/1471-2105-7-150 |