Lung fibroblasts from patients with emphysema show markers of senescence in vitro

BACKGROUND: The loss of alveolar walls is a hallmark of emphysema. As fibroblasts play an important role in the maintenance of alveolar structure, a change in fibroblast phenotype could be involved in the pathogenesis of this disease. In a previous study we found a reduced in vitro proliferation rat...

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Detalles Bibliográficos
Autores principales: Müller, K-C, Welker, L, Paasch, K, Feindt, B, Erpenbeck, VJ, Hohlfeld, JM, Krug, N, Nakashima, M, Branscheid, D, Magnussen, H, Jörres, RA, Holz, O
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435750/
https://www.ncbi.nlm.nih.gov/pubmed/16504044
http://dx.doi.org/10.1186/1465-9921-7-32

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