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Statistical deconvolution of enthalpic energetic contributions to MHC-peptide binding affinity
BACKGROUND: MHC Class I molecules present antigenic peptides to cytotoxic T cells, which forms an integral part of the adaptive immune response. Peptides are bound within a groove formed by the MHC heavy chain. Previous approaches to MHC Class I-peptide binding prediction have largely concentrated o...
Autores principales: | Davies, Matthew N, Hattotuwagama, Channa K, Moss, David S, Drew, Michael GB, Flower, Darren R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435758/ https://www.ncbi.nlm.nih.gov/pubmed/16549002 http://dx.doi.org/10.1186/1472-6807-6-5 |
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