Amplification of the Gene Ontology annotation of Affymetrix probe sets

BACKGROUND: The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete annotations which is not always desirable for microarray experiment evaluation. RESULTS: Here we present a protocol to amp...

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Detalles Bibliográficos
Autores principales: Muro, Enrique M, Perez-Iratxeta, Carolina, Andrade-Navarro, Miguel A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435773/
https://www.ncbi.nlm.nih.gov/pubmed/16549014
http://dx.doi.org/10.1186/1471-2105-7-159
Descripción
Sumario:BACKGROUND: The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete annotations which is not always desirable for microarray experiment evaluation. RESULTS: Here we present a protocol to amplify the set of Gene Ontology annotations associated to Affymetrix DNA microarray probe sets using information from related databases. CONCLUSION: Predicted novel annotations and the evidence producing them can be accessed at Probe2GO: . Scripts are available on demand.

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