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Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21
BACKGROUND: Down syndrome (DS) is caused by trisomy 21 (+21), but the aberrations in gene expression resulting from this chromosomal aneuploidy are not yet completely understood. METHODS: We used oligonucleotide microarrays to survey mRNA expression in early- and late-passage control and +21 fibrobl...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435874/ https://www.ncbi.nlm.nih.gov/pubmed/16539728 http://dx.doi.org/10.1186/1471-2350-7-24 |