IL-4 induced MUC4 enhancement in respiratory epithelial cells in vitro is mediated through JAK-3 selective signaling

BACKGROUND: Recent studies have identified MUC4 mucin as a ligand for activation of ErbB2, a receptor tyrosine kinase that modulates epithelial cell proliferation following epithelial damage in airways of asthmatics. In this study, we investigated the potential role of IL-4, one of the Th2 inflammat...

Descripción completa

Detalles Bibliográficos
Autores principales: Damera, Gautam, Xia, Baoyun, Sachdev, Goverdhan P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435893/
https://www.ncbi.nlm.nih.gov/pubmed/16551361
http://dx.doi.org/10.1186/1465-9921-7-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435893/
https://www.ncbi.nlm.nih.gov/pubmed/16551361
http://dx.doi.org/10.1186/1465-9921-7-39

Ejemplares similares