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Alternating current electrical stimulation enhanced chemotherapy: a novel strategy to bypass multidrug resistance in tumor cells

BACKGROUND: Tumor burden can be pharmacologically controlled by inhibiting cell division and by direct, specific toxicity to the cancerous tissue. Unfortunately, tumors often develop intrinsic pharmacoresistance mediated by specialized drug extrusion mechanisms such as P-glycoprotein. As a consequen...

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Detalles Bibliográficos
Autores principales: Janigro, Damir, Perju, Catalin, Fazio, Vincent, Hallene, Kerri, Dini, Gabriele, Agarwal, Mukesh K, Cucullo, Luca
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435916/
https://www.ncbi.nlm.nih.gov/pubmed/16545134
http://dx.doi.org/10.1186/1471-2407-6-72