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Monensin Improves the Effectiveness of meso-Dimercaptosuccinate when Used to Treat Lead Intoxication in Rats
Among divalent cations, the ionophore monensin shows high activity and selectivity for the transport of lead ions (Pb(2+)) across phospholipid membranes. When coadministered to rats that were receiving meso-dimercaptosuccinate for treatment of Pb intoxication, monensin significantly increased the am...
Autores principales: | Hamidinia, Shawn A., Erdahl, Warren L., Chapman, Clifford J., Steinbaugh, Gregory E., Taylor, Richard W., Pfeiffer, Douglas R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440769/ https://www.ncbi.nlm.nih.gov/pubmed/16581534 http://dx.doi.org/10.1289/ehp.8279 |
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