Stage-variations of anandamide hydrolase activity in the mouse uterus during the natural oestrus cycle

Recent studies have demonstrated that the endogenous cannabinoids are important modulators of fertility in mammals. In particular, a role of the endocannabinoid system in early stages of embryo development, oviductal transport of embryos, pregnancy maintenance and labour has been demonstrated in rod...

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Detalles Bibliográficos
Autores principales: Klinger, Francesca G, Battista, Natalia, De Felici, Massimo, Maccarrone, Mauro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440866/
https://www.ncbi.nlm.nih.gov/pubmed/16573810
http://dx.doi.org/10.1186/1743-1050-3-3
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author Klinger, Francesca G
Battista, Natalia
De Felici, Massimo
Maccarrone, Mauro
author_facet Klinger, Francesca G
Battista, Natalia
De Felici, Massimo
Maccarrone, Mauro
author_sort Klinger, Francesca G
collection PubMed
description Recent studies have demonstrated that the endogenous cannabinoids are important modulators of fertility in mammals. In particular, a role of the endocannabinoid system in early stages of embryo development, oviductal transport of embryos, pregnancy maintenance and labour has been demonstrated in rodents and/or in humans. In the present paper, we report the analysis of FAAH activity and protein content in the mouse uterus as a function of the natural oestrus cycle stages. Variations of FAAH activity are discussed in relationship to changes in sex steroid levels and to the possible action of AEA on remodelling of uterine tissues.
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spelling pubmed-14408662006-04-20 Stage-variations of anandamide hydrolase activity in the mouse uterus during the natural oestrus cycle Klinger, Francesca G Battista, Natalia De Felici, Massimo Maccarrone, Mauro J Exp Clin Assist Reprod Hypothesis Recent studies have demonstrated that the endogenous cannabinoids are important modulators of fertility in mammals. In particular, a role of the endocannabinoid system in early stages of embryo development, oviductal transport of embryos, pregnancy maintenance and labour has been demonstrated in rodents and/or in humans. In the present paper, we report the analysis of FAAH activity and protein content in the mouse uterus as a function of the natural oestrus cycle stages. Variations of FAAH activity are discussed in relationship to changes in sex steroid levels and to the possible action of AEA on remodelling of uterine tissues. BioMed Central 2006-03-30 /pmc/articles/PMC1440866/ /pubmed/16573810 http://dx.doi.org/10.1186/1743-1050-3-3 Text en Copyright © 2006 Klinger et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Hypothesis
Klinger, Francesca G
Battista, Natalia
De Felici, Massimo
Maccarrone, Mauro
Stage-variations of anandamide hydrolase activity in the mouse uterus during the natural oestrus cycle
title Stage-variations of anandamide hydrolase activity in the mouse uterus during the natural oestrus cycle
title_full Stage-variations of anandamide hydrolase activity in the mouse uterus during the natural oestrus cycle
title_fullStr Stage-variations of anandamide hydrolase activity in the mouse uterus during the natural oestrus cycle
title_full_unstemmed Stage-variations of anandamide hydrolase activity in the mouse uterus during the natural oestrus cycle
title_short Stage-variations of anandamide hydrolase activity in the mouse uterus during the natural oestrus cycle
title_sort stage-variations of anandamide hydrolase activity in the mouse uterus during the natural oestrus cycle
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440866/
https://www.ncbi.nlm.nih.gov/pubmed/16573810
http://dx.doi.org/10.1186/1743-1050-3-3
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AT defelicimassimo stagevariationsofanandamidehydrolaseactivityinthemouseuterusduringthenaturaloestruscycle
AT maccarronemauro stagevariationsofanandamidehydrolaseactivityinthemouseuterusduringthenaturaloestruscycle

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