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Dominant negative retinoic acid receptor initiates tumor formation in mice

BACKGROUND: Retinoic acid suppresses cell growth and promotes cell differentiation, and pharmacological retinoic acid receptor (RAR) activation is anti-tumorigenic. This begs the question of whether chronic physiological RAR activation by endogenous retinoids is likewise anti-tumorigenic. RESULTS: T...

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Detalles Bibliográficos
Autores principales:	Kupumbati, Tara S, Cattoretti, Giorgio, Marzan, Christine, Farias, Eduardo F, Taneja, Reshma, Mira-y-Lopez, Rafael
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1444935/ https://www.ncbi.nlm.nih.gov/pubmed/16563162 http://dx.doi.org/10.1186/1476-4598-5-12

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