Post-genomics of the model haloarchaeon Halobacterium sp. NRC-1

Halobacteriumsp. NRC-1 is an extremely halophilic archaeon that is easily cultured and genetically tractable. Since its genome sequence was completed in 2000, a combination of genetic, transcriptomic, proteomic, and bioinformatic approaches have provided insights into both its extremophilic lifestyl...

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Autores principales: DasSarma, Shiladitya, Berquist, Brian R, Coker, James A, DasSarma, Priya, Müller, Jochen A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1447603/
https://www.ncbi.nlm.nih.gov/pubmed/16542428
http://dx.doi.org/10.1186/1746-1448-2-3
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author DasSarma, Shiladitya
Berquist, Brian R
Coker, James A
DasSarma, Priya
Müller, Jochen A
author_facet DasSarma, Shiladitya
Berquist, Brian R
Coker, James A
DasSarma, Priya
Müller, Jochen A
author_sort DasSarma, Shiladitya
collection PubMed
description Halobacteriumsp. NRC-1 is an extremely halophilic archaeon that is easily cultured and genetically tractable. Since its genome sequence was completed in 2000, a combination of genetic, transcriptomic, proteomic, and bioinformatic approaches have provided insights into both its extremophilic lifestyle as well as fundamental cellular processes common to all life forms. Here, we review post-genomic research on this archaeon, including investigations of DNA replication and repair systems, phototrophic, anaerobic, and other physiological capabilities, acidity of the proteome for function at high salinity, and role of lateral gene transfer in its evolution.
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spelling pubmed-14476032006-04-26 Post-genomics of the model haloarchaeon Halobacterium sp. NRC-1 DasSarma, Shiladitya Berquist, Brian R Coker, James A DasSarma, Priya Müller, Jochen A Saline Syst Review Halobacteriumsp. NRC-1 is an extremely halophilic archaeon that is easily cultured and genetically tractable. Since its genome sequence was completed in 2000, a combination of genetic, transcriptomic, proteomic, and bioinformatic approaches have provided insights into both its extremophilic lifestyle as well as fundamental cellular processes common to all life forms. Here, we review post-genomic research on this archaeon, including investigations of DNA replication and repair systems, phototrophic, anaerobic, and other physiological capabilities, acidity of the proteome for function at high salinity, and role of lateral gene transfer in its evolution. BioMed Central 2006-03-16 /pmc/articles/PMC1447603/ /pubmed/16542428 http://dx.doi.org/10.1186/1746-1448-2-3 Text en Copyright © 2006 DasSarma et al; licensee BioMed Central Ltd. https://creativecommons.org/licenses/by/2.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0 (https://creativecommons.org/licenses/by/2.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
DasSarma, Shiladitya
Berquist, Brian R
Coker, James A
DasSarma, Priya
Müller, Jochen A
Post-genomics of the model haloarchaeon Halobacterium sp. NRC-1
title Post-genomics of the model haloarchaeon Halobacterium sp. NRC-1
title_full Post-genomics of the model haloarchaeon Halobacterium sp. NRC-1
title_fullStr Post-genomics of the model haloarchaeon Halobacterium sp. NRC-1
title_full_unstemmed Post-genomics of the model haloarchaeon Halobacterium sp. NRC-1
title_short Post-genomics of the model haloarchaeon Halobacterium sp. NRC-1
title_sort post-genomics of the model haloarchaeon halobacterium sp. nrc-1
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1447603/
https://www.ncbi.nlm.nih.gov/pubmed/16542428
http://dx.doi.org/10.1186/1746-1448-2-3
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