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High-grade symptomatic and asymptomatic carotid stenosis in the very elderly. A challenge for proponents of carotid angioplasty and stenting

BACKGROUND: Carotid angioplasty and stenting (CAS) is often considered as the preferred treatment for severe carotid occlusive disease in patients labelled as "high risk", including those aged 80 or more. We analyzed 30-day stroke risk and death rates after carotid endarterectomy (CEA) for...

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Autores principales: Ballotta, Enzo, Da Giau, Giuseppe, Militello, Carmelo, Barbon, Bruno, De Rossi, Aldo, Meneghetti, Giorgio, Baracchini, Claudio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448179/
https://www.ncbi.nlm.nih.gov/pubmed/16573829
http://dx.doi.org/10.1186/1471-2261-6-12
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author Ballotta, Enzo
Da Giau, Giuseppe
Militello, Carmelo
Barbon, Bruno
De Rossi, Aldo
Meneghetti, Giorgio
Baracchini, Claudio
author_facet Ballotta, Enzo
Da Giau, Giuseppe
Militello, Carmelo
Barbon, Bruno
De Rossi, Aldo
Meneghetti, Giorgio
Baracchini, Claudio
author_sort Ballotta, Enzo
collection PubMed
description BACKGROUND: Carotid angioplasty and stenting (CAS) is often considered as the preferred treatment for severe carotid occlusive disease in patients labelled as "high risk", including those aged 80 or more. We analyzed 30-day stroke risk and death rates after carotid endarterectomy (CEA) for severe symptomatic or asymptomatic carotid disease in patients aged 80 or more, by comparison with the outcome of CAS reported in the recently- published literature. METHODS: A retrospective review was conducted on a prospectively compiled computerized database of all primary CEAs performed by a single surgeon at our institution from 1990 to 2003. Descriptive demographic data, risk factors, surgical details, perioperative strokes and deaths, and other complications were recorded. RESULTS: In all, 1260 CEAs were performed in 1099 patients; 1145 were performed in 987 patients less than 80 years old, and 115 were performed in 112 patients aged 80 or more. There were 11 perioperative strokes in the 1145 procedures in the younger group, for a stroke rate of 0.8%, and no strokes in the 115 procedures in the older group. The death rates were 0% for the octogenarians and 0.3% for the younger group. CONCLUSION: The conviction that older age means higher risk needs to be revised. Patients aged 80 or more can undergo CEA with no more perioperative risks than younger patients. Proponents of CAS should bear this in mind before recommending CAS as the best therapeutic option for such patients.
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spelling pubmed-14481792006-04-27 High-grade symptomatic and asymptomatic carotid stenosis in the very elderly. A challenge for proponents of carotid angioplasty and stenting Ballotta, Enzo Da Giau, Giuseppe Militello, Carmelo Barbon, Bruno De Rossi, Aldo Meneghetti, Giorgio Baracchini, Claudio BMC Cardiovasc Disord Research Article BACKGROUND: Carotid angioplasty and stenting (CAS) is often considered as the preferred treatment for severe carotid occlusive disease in patients labelled as "high risk", including those aged 80 or more. We analyzed 30-day stroke risk and death rates after carotid endarterectomy (CEA) for severe symptomatic or asymptomatic carotid disease in patients aged 80 or more, by comparison with the outcome of CAS reported in the recently- published literature. METHODS: A retrospective review was conducted on a prospectively compiled computerized database of all primary CEAs performed by a single surgeon at our institution from 1990 to 2003. Descriptive demographic data, risk factors, surgical details, perioperative strokes and deaths, and other complications were recorded. RESULTS: In all, 1260 CEAs were performed in 1099 patients; 1145 were performed in 987 patients less than 80 years old, and 115 were performed in 112 patients aged 80 or more. There were 11 perioperative strokes in the 1145 procedures in the younger group, for a stroke rate of 0.8%, and no strokes in the 115 procedures in the older group. The death rates were 0% for the octogenarians and 0.3% for the younger group. CONCLUSION: The conviction that older age means higher risk needs to be revised. Patients aged 80 or more can undergo CEA with no more perioperative risks than younger patients. Proponents of CAS should bear this in mind before recommending CAS as the best therapeutic option for such patients. BioMed Central 2006-03-30 /pmc/articles/PMC1448179/ /pubmed/16573829 http://dx.doi.org/10.1186/1471-2261-6-12 Text en Copyright © 2006 Ballotta et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Ballotta, Enzo
Da Giau, Giuseppe
Militello, Carmelo
Barbon, Bruno
De Rossi, Aldo
Meneghetti, Giorgio
Baracchini, Claudio
High-grade symptomatic and asymptomatic carotid stenosis in the very elderly. A challenge for proponents of carotid angioplasty and stenting
title High-grade symptomatic and asymptomatic carotid stenosis in the very elderly. A challenge for proponents of carotid angioplasty and stenting
title_full High-grade symptomatic and asymptomatic carotid stenosis in the very elderly. A challenge for proponents of carotid angioplasty and stenting
title_fullStr High-grade symptomatic and asymptomatic carotid stenosis in the very elderly. A challenge for proponents of carotid angioplasty and stenting
title_full_unstemmed High-grade symptomatic and asymptomatic carotid stenosis in the very elderly. A challenge for proponents of carotid angioplasty and stenting
title_short High-grade symptomatic and asymptomatic carotid stenosis in the very elderly. A challenge for proponents of carotid angioplasty and stenting
title_sort high-grade symptomatic and asymptomatic carotid stenosis in the very elderly. a challenge for proponents of carotid angioplasty and stenting
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448179/
https://www.ncbi.nlm.nih.gov/pubmed/16573829
http://dx.doi.org/10.1186/1471-2261-6-12
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