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LMP-420, a small-molecule inhibitor of TNF-alpha, reduces replication of HIV-1 and Mycobacterium tuberculosis in human cells
BACKGROUND: Co-infections of human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (M. Tb) are steadily increasing and represent a major health crisis in many developing countries. Both pathogens individually stimulate tumor necrosis factor-alpha (TNF) release from infected cells and TNF...
Autores principales: | Haraguchi, Soichi, Day, Noorbibi K, Kamchaisatian, Wasu, Beigier-Pompadre, Macarena, Stenger, Steffen, Tangsinmankong, Nutthapong, Sleasman, John W, Pizzo, Salvatore V, Cianciolo, George J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1448187/ https://www.ncbi.nlm.nih.gov/pubmed/16573838 http://dx.doi.org/10.1186/1742-6405-3-8 |
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