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Crystallographic identification of an ordered C-terminal domain and a second nucleotide-binding site in RecA: new insights into allostery

RecA protein is a crucial and central component of the homologous recombination and DNA repair machinery. Despite numerous studies on the protein, several issues concerning its action, including the allosteric regulation mechanism have remained unclear. Here we report, for the first time, a crystal...

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Detalles Bibliográficos
Autores principales: Krishna, R., Manjunath, G. P., Kumar, P., Surolia, A., Chandra, Nagasuma R., Muniyappa, K., Vijayan, M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450331/
https://www.ncbi.nlm.nih.gov/pubmed/16648362
http://dx.doi.org/10.1093/nar/gkl107