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Promoter analysis by saturation mutagenesis
Gene expression and regulation are mediated by DNA sequences, in most instances, directly upstream to the coding sequences by recruiting transcription factors, regulators, and a RNA polymerase in a spatially defined fashion. Few nucleotides within a promoter make contact with the bound proteins. The...
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Formato: | Texto |
Lenguaje: | English |
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Biological Procedures Online
2001
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC145547/ https://www.ncbi.nlm.nih.gov/pubmed/12734578 http://dx.doi.org/10.1251/bpo24 |