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Novel method for high throughput DNA methylation marker evaluation using PNA-probe library hybridization and MALDI-TOF detection
The methylation of CpG dinucleotides has become a topic of great interest in cancer research, and the methylation of promoter regions of several tumor suppressor genes has been identified as a marker of tumorigenesis. Evaluation of DNA methylation markers in tumor tissue requires hundreds of samples...
Autores principales: | Schatz, Philipp, Distler, Jürgen, Berlin, Kurt, Schuster, Matthias |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456329/ https://www.ncbi.nlm.nih.gov/pubmed/16670426 http://dx.doi.org/10.1093/nar/gkl218 |
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