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A clustering property of highly-degenerate transcription factor binding sites in the mammalian genome
Transcription factor binding sites (TFBSs) are short DNA sequences interacting with transcription factors (TFs), which regulate gene expression. Due to the relatively short length of such binding sites, it is largely unclear how the specificity of protein–DNA interaction is achieved. Here, we have p...
Autores principales: | Zhang, Chaolin, Xuan, Zhenyu, Otto, Stefanie, Hover, John R., McCorkle, Sean R., Mandel, Gail, Zhang, Michael Q. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456330/ https://www.ncbi.nlm.nih.gov/pubmed/16670430 http://dx.doi.org/10.1093/nar/gkl248 |
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