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The quantification of COMT mRNA in post mortem cerebellum tissue: diagnosis, genotype, methylation and expression

BACKGROUND: The COMT gene is located on chromosome 22q11, a region strongly implicated in the aetiology of several psychiatric disorders, in particular schizophrenia. Previous research has suggested that activity and expression of COMT is altered in schizophrenia, and is mediated by one or more poly...

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Detalles Bibliográficos
Autores principales: Dempster, Emma L, Mill, Jonathan, Craig, Ian W, Collier, David A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456954/
https://www.ncbi.nlm.nih.gov/pubmed/16483362
http://dx.doi.org/10.1186/1471-2350-7-10

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