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Overexpression of endothelial nitric oxide synthase suppresses features of allergic asthma in mice

BACKGROUND: Asthma is associated with airway hyperresponsiveness and enhanced T-cell number/activity on one hand and increased levels of exhaled nitric oxide (NO) with expression of inducible NO synthase (iNOS) on the other hand. These findings are in paradox, as NO also relaxes airway smooth muscle...

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Detalles Bibliográficos
Autores principales: Broeke, Robert Ten, De Crom, Rini, Van Haperen, Rien, Verweij, Vivienne, Leusink-Muis, Thea, Van Ark, Ingrid, De Clerck, Fred, Nijkamp, Frans P, Folkerts, Gert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1456969/
https://www.ncbi.nlm.nih.gov/pubmed/16597326
http://dx.doi.org/10.1186/1465-9921-7-58